Jurkat cells were subjected to SDS PAGE followed by western blot with FNab06971(PYCR2 antibody) at dilution of 1:5000
IP Result of anti-PYCR2 (IP:FNab06971, 4ug; Detection:FNab06971 1:500) with Jurkat cells lysate 2400ug.
Immunohistochemistry of paraffin-embedded human ovary using FNab06971(PYCR2 antibody) at dilution of 1:50
Background
Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH(PubMed:2722838, PubMed:6894153). Involved in cellular response to oxidative stress(PubMed:25865492).