PYCR2 antibody

Catalogue No.:FNab06971Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IF, IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
PYCR2 antibody
Catalogue No.
FNab06971
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
pyrroline-5-carboxylate reductase family, member 2
UniProt ID
Q96C36
Observed MW
34 kDa
Application
Tested Applications
ELISA, WB, IHC, IF, IP
Recommended dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab06971(PYCR2 antibody) at dilution of 1:5000
IP Result of anti-PYCR2 (IP:FNab06971, 4ug; Detection:FNab06971 1:500) with Jurkat cells lysate 2400ug.
Immunohistochemistry of paraffin-embedded human ovary using FNab06971(PYCR2 antibody) at dilution of 1:50
Background
Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH(PubMed:2722838, PubMed:6894153). Involved in cellular response to oxidative stress(PubMed:25865492).