Products
PTPRS antibody
- Product Name
- PTPRS antibody
- Catalogue No.
- FNab06948
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- protein tyrosine phosphatase, receptor type, S
- UniProt ID
- Q13332
- Observed MW
- 75-100 kDa,220 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IP, FC
- Recommended dilution
- WB: 1:200-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab06948(rPTP?? antibody) at dilution of 1:1000
IP Result of anti-PTPRS (IP:FNab06948, 5ug; Detection:FNab06948 1:400) with mouse brain tissue lysate 6500ug.
Immunohistochemistry of paraffin-embedded human ovary tumor using FNab06948(rPTP?? antibody) at dilution of 1:100
- Background
- Type II a receptor protein tyrosine phosphatases (rPTPσ) are cell surface receptors important for nervous system development, function, and repair.The expression of rPTPσ has previously been reported in b-cells and other target organs for INS although the probes chosen did not permit to distinguish between the splice variants.Proteolytic processing near the transmembrane domain generates an extracellular N-terminal E-domain of 130 kDa and a C-terminal P-domain of approximately 85 kDa of rPTPσ,and the short splice variants rPTPσ 3 and 4 contain an E-domain of 95 kDa (PMID: 16552719). rPTPσ expression was observed in tissue lysates of the adult mouse sensory-motor cortex and thoracic spinal cord (T8-T10) as a 75-80kDa immunoreactive band (PMID: 19780196).
