Products
PTPN23 antibody
- Product Name
- PTPN23 antibody
- Catalogue No.
- FNab06937
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- protein tyrosine phosphatase, non-receptor type 23
- Alternative Names
- KIAA1471 antibody
- UniProt ID
- Q9H3S7
- Observed MW
- 179 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IP
- Recommended dilution
- WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:100-1:400; IF: 1:50-1:500
Validated Images
A375 cells were subjected to SDS PAGE followed by western blot with FNab06937(PTPN23 antibody) at dilution of 1:500
IP Result of anti-PTPN23 (IP:FNab06937, 5ug; Detection:FNab06937 1:500) with HeLa cells lysate 1000ug.
Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using FNab06937(PTPN23 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
- Background
- Plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies(MVBs) via its interaction with the ESCRT-I complex(endosomal sorting complex required for transport I), and possibly also other ESCRT complexes. May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis.
