HepG2 cells were subjected to SDS PAGE followed by western blot with FNab06791( PRMT5 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat brain using FNab06791( PRMT5 Antibody) at dilution of 1:50
Background
This gene encodes an enzyme that belongs to the methyltransferase family. The encoded protein catalyzes the transfer of methyl groups to the amino acid arginine, in target proteins that include histones, transcriptional elongation factors and the tumor suppressor p53. This gene plays a role in several cellular processes, including transcriptional regulation, and the assembly of small nuclear ribonucleoproteins. A pseudogene of this gene has been defined on chromosome 4. Alternative splicing results in multiple transcript variants encoding different isoforms.