Products

Prealbumin/transthyretin antibody

Synonyms:ATTR antibody, HsT2651 antibody, PALB antibody, Prealbumin antibody, TBPA antibody, transthyretin antibody, TTR antibody
Catalogue No.:FNab06760Reativity:Human, Mouse
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
Prealbumin/transthyretin antibody
Catalogue No.
FNab06760
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
transthyretin
Alternative Names
ATTR antibody, HsT2651 antibody, PALB antibody, Prealbumin antibody, TBPA antibody, transthyretin antibody, TTR antibody
UniProt ID
P02766
Observed MW
14 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab06760(TTR antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver cancer using FNab06760(TTR antibody) at dilution of 1:100
Background
This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.