Products
PPARA antibody
- Product Name
- PPARA antibody
- Catalogue No.
- FNab06663
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- peroxisome proliferator-activated receptor alpha
- Alternative Names
- hPPAR antibody, NR1C1 antibody, PPAR antibody, PPAR alpha antibody, PPARA antibody
- UniProt ID
- Q07869
- Observed MW
- 52-55 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:200-1:1000; IHC: 1:50-1:200
Validated Images
U-937 cells were subjected to SDS PAGE followed by western blot with FNab06663(PPARA antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue slide using FNab06663(PPARA Antibody) at dilution of 1:100
- Background
- Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine(16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.
