Products

anti- PLEKHA8 antibody

FNab06537 Catalogue No.
Synonyms
FAPP2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Isotype
IgG
Tested Application
ELISA, WB, IHC
Product Information
Product Name
anti- PLEKHA8 antibody
Catalogue No.
FNab06537
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
Cargo transport protein that is required for apical transport from the Golgi complex. Transports AQP2 from the trans-Golgi network(TGN) to sites of AQP2 phosphorylation. Mediates the non-vesicular transport of glucosylceramide(GlcCer) from the trans-Golgi network(TGN) to the plasma membrane and plays a pivotal role in the synthesis of complex glycosphingolipids. Binding of both phosphatidylinositol 4-phosphate(PIP) and ARF1 are essential for the GlcCer transfer ability. Also required for primary cilium formation, possibly by being involved in the transport of raft lipids to the apical membrane, and for membrane tubulation.
Immunogen Information
Immunogen
pleckstrin homology domain containing, family A(phosphoinositide binding specific) member 8
Synonyms
FAPP2
Observed MW
49 kDa
Application
Tested Application
ELISA, WB, IHC
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Uniprot information
UniProt ID
Q96JA3
Images
Immunohistochemistry of paraffin-embedded human kidney using FNab06537(PLEKHA8 antibody) at dilution of 1:50
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab06537(PLEKHA8 antibody) at dilution of 1:800