MCF7 cells were subjected to SDS PAGE followed by western blot with FNab04254(IL22RA2 Antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab04254( IL22RA2 antibody) at dilution of 1:200
Background
Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22(in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses.Isoform 1 may play a role in establishing and maintaining successful pregnancy.