Neuro-2a cells were subjected to SDS PAGE followed by western blot with FNab06409(PHOX2B Antibody) at dilution of 1:2500
Immunohistochemistry of paraffin-embedded neuroblastoma tissue slide using FNab06409(PHOX2B Antibody) at dilution of 1:50
Background
Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum-response element.