Products
PDCD4 antibody
- Product Name
- PDCD4 antibody
- Catalogue No.
- FNab06240
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG1
- Clone ID
- 3B7
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- programmed cell death 4(neoplastic transformation inhibitor)
- Alternative Names
- H731 antibody, Nuclear antigen H731 like antibody, PDCD4 antibody, Protein 197/15a antibody
- UniProt ID
- Q53EL6
- Observed MW
- 56 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:1000-1:4000; IHC: 1:20-1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab06240(PDCD4 Antibody) at dilution of 1:2000
Immunohistochemistry of paraffin-embedded human breast cancer slide using FNab06240(PDCD4 Antibody) at dilution of 1:50
- Background
- Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA(By similarity).
