Products
PAX6 antibody
- Product Name
- PAX6 antibody
- Catalogue No.
- FNab06172
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- paired box 6
- Alternative Names
- AN antibody, AN2 antibody, Aniridia type II protein antibody, D11S812E antibody, MGDA antibody, Oculorhombin antibody, paired box 6 antibody, Paired box protein Pax 6 antibody, PAX6 antibody, WAGR antibody
- UniProt ID
- P26367
- Observed MW
- 47kd
Application
- Tested Applications
- ELISA, IHC, WB
- Recommended dilution
- WB: 1:300-1:1200; IHC: 1:50-1:500; IF: 1:50-1:500
Validated Images
Y79 cells were subjected to SDS PAGE followed by western blot with FNab06172(PAX6 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded mouse embryo tissue slide using FNab06172(PAX6 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
- Background
- Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells(By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains(By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes.
