PAICS antibody

Synonyms:ADE2 antibody, AIRC antibody, PAIS antibody
Catalogue No.:FNab06115Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, IHC, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
PAICS antibody
Catalogue No.
FNab06115
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
Alternative Names
ADE2 antibody, AIRC antibody, PAIS antibody
UniProt ID
P22234
Observed MW
45 kDa
Application
Tested Applications
ELISA, IHC, WB
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab06115(PAICS antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat spleen using FNab06115(PAICS antibody) at dilution of 1:100
Background
This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.