A375 cells were subjected to SDS PAGE followed by western blot with FNab06071(P2RX7 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human kidney slide using FNab06071(P2RX7 antibody) at dilution of 1:50
Background
Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.