NUDT21 antibody

Category: Research Area:
Synonyms：CFIM25 antibody, CPSF25 antibody, CPSF5 antibody
Catalogue No.：FNab05904Reactivity：Human, Mouse, Rat
Host：RabbitTested Application：ELISA, WB, IHC, IF, IP
Clonality：polyclonalIsotype：IgG
Manual MSDS
  • SPECIFICATIONS
Product Name
NUDT21 antibody
Catalogue No.
FNab05904
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
nudix(nucleoside diphosphate linked moiety X)-type motif 21
Alternative Names
CFIM25 antibody, CPSF25 antibody, CPSF5 antibody
UniProt ID
O43809
Observed MW
26 kDa
Application
Tested Applications
ELISA, WB, IHC, IF, IP
Recommended dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
human brain tissue were subjected to SDS PAGE followed by western blot with FNab05904(NUDT21 antibody) at dilution of 1:500
IP Result of anti-NUDT21 (IP:FNab05904, 3ug; Detection:FNab05904 1:500) with HeLa cells lysate 3000ug.
Immunohistochemistry of paraffin-embedded human placenta using FNab05904(NUDT21 antibody) at dilution of 1:50
Background
Component of the cleavage factor Im(CFIm) complex that plays a key role in pre-mRNA 3'-processing. Involved in association with CPSF6 or CPSF7 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. NUDT21/CPSF5 binds to cleavage and polyadenylation RNA substrates. The homodimer mediates simultaneous sequence-specific recognition of two 5'-UGUA-3' elements within the pre-mRNA. Binds to, but does not hydrolyze mono-and di-adenosine nucleotides. May have a role in mRNA export.
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