Products
NPHP5,IQCB1 antibody
- Product Name
- NPHP5,IQCB1 antibody
- Catalogue No.
- FNab05818
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- IQ motif containing B1
- Alternative Names
- IQ motif containing B1 antibody, IQCB1 antibody, KIAA0036 antibody, Nephrocystin 5 antibody, NPHP5 antibody, PIQ antibody, SLSN5 antibody
- UniProt ID
- Q15051
Application
- Tested Applications
- ELISA, IF
- Recommended dilution
- IF: 1:10-1:100
Validated Images
IF Result of anti-NPHP5 (FNab05818,1:50) show 'focal adhesion-like' structures in human hTERT-RPE1 cells. 1% PFA fixation.
- Background
- IQCB1, also known as NPHP5, is a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. It has a central coiled-coil region and two calmodulin-binding IQ domains. Localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells, IQCB1 is thought to play a role in ciliary function. Mutations in this gene result in Senior-Loken syndrome type 5, a juvenile disorder characterized by defects in the waste filtering system of the kidney, as well as retinal degradation.
