Products
NPHP3 antibody
- Product Name
- NPHP3 antibody
- Catalogue No.
- FNab05816
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- nephronophthisis 3(adolescent)
- Alternative Names
- KIAA2000 antibody
- UniProt ID
- Q7Z494
- Observed MW
- 145-151 kDa
Application
- Tested Applications
- ELISA, WB, IF, IHC, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
human testis tissue were subjected to SDS PAGE followed by western blot with FNab05816(NPHP3 antibody) at dilution of 1:500
IP Result of anti-NPHP3 (IP:FNab05816, 4ug; Detection:FNab05816 1:1000) with mouse testis tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human heart tissue slide using FNab05816(NPHP3 Antibody) at dilution of 1:50
- Background
- Required for normal ciliary development and function. Inhibits disheveled-1-induced canonical Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling which regulates planar cell polarity. Probably acts as a molecular switch between different Wnt signaling pathways. Required for proper convergent extension cell movements.
