Products
MLYCD antibody
- Product Name
- MLYCD antibody
- Catalogue No.
- FNab05225
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- malonyl-CoA decarboxylase
- UniProt ID
- O95822
- Observed MW
- 50kd,55kd,66kd
Application
- Tested Applications
- ELISA, WB, IHC, IF, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
human testis tissue were subjected to SDS PAGE followed by western blot with FNab05225(MLYCD antibody) at dilution of 1:400
IP Result of anti-MLYCD (IP:FNab05225, 4ug; Detection:FNab05225 1:500) with mouse heart tissue lysate 5000ug.
Immunohistochemistry of paraffin-embedded human kidney using FNab05225(MLYCD antibody) at dilution of 1:50
- Background
- Catalyzes the conversion of malonyl-CoA to acetyl-CoA. In the fatty acid biosynthesis MCD selectively removes malonyl-CoA and thus assures that methyl-malonyl-CoA is the only chain elongating substrate for fatty acid synthase and that fatty acids with multiple methyl side chains are produced. In peroxisomes it may be involved in degrading intraperoxisomal malonyl-CoA, which is generated by the peroxisomal beta-oxidation of odd chain-length dicarboxylic fatty acids. Plays a role in the metabolic balance between glucose and lipid oxidation in muscle independent of alterations in insulin signaling. May play a role in controlling the extent of ischemic injury by promoting glucose oxidation.
