Products

anti- Zyxin antibody

FNab09765 Catalogue No.
Synonyms
ESP 2, HED 2, ZYX, zyxin, Zyxin 2
Host
Mouse
Reactivity
Human, Mouse
Isotype
IgG1
Tested Application
ELISA, WB, IHC, IF
Product Information
Product Name
anti- Zyxin antibody
Catalogue No.
FNab09765
Size
100µg
Form
liquid
Purification
Protein A+G purification
Purity
≥95% as determined by SDS-PAGE
Host
Mouse
Clonality
monoclonal
Isotype
IgG1
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin (ZYX) is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles.
Immunogen Information
Immunogen
zyxin
Synonyms
ESP 2, HED 2, ZYX, zyxin, Zyxin 2
Observed MW
80 kDa
Application
Tested Application
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:20-1:200
Uniprot information
UniProt ID
Q15942
Images
Immunohistochemistry of paraffin-embedded human kidney slide using FNab09765 (ZYX Antibody) at dilution of 1:50
Immunofluorescent analysis of HeLa cells using FNab09765(ZYX Antibody) at dilution of 1:50
HeLa cells were subjected to SDS PAGE followed by western blot with FNab09765 (ZYX antibody) at dilution of 1:1000