Products
MEX3C antibody
- Product Name
- MEX3C antibody
- Catalogue No.
- FNab05145
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- mex-3 homolog C(C. elegans)
- Alternative Names
- RKHD2 antibody, RNF194 antibody
- UniProt ID
- Q5U5Q3
- Observed MW
- 69 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab05145(MEX3C antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human testis tissue slide using FNab05145(MEX3C Antibody) at dilution of 1:50
- Background
- E3 ubiquitin ligase responsible for the post-transcriptional regulation of common HLA-A allotypes. Binds to the 3' UTR of HLA-A2 mRNA, and regulates its levels by promoting mRNA decay. RNA binding is sufficient to prevent translation, but ubiquitin ligase activity is required for mRNA degradation.
