MCL1 antibody

Synonyms:BCL2L3 antibody
Catalogue No.:FNab05053Reactivity:Human
Host:MouseTested Application:ELISA, WB, IF, IHC
Clonality:monoclonalIsotype:IgG2a
  • SPECIFICATIONS
Product Name
MCL1 antibody
Catalogue No.
FNab05053
Size
100μg
Form
liquid
Purification
Protein A+G purification
Purity
≥95% as determined by SDS-PAGE
Clonality
monoclonal
Isotype
IgG2a
Clone ID
6F10
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
myeloid cell leukemia sequence 1(BCL2-related)
Alternative Names
BCL2L3 antibody
UniProt ID
Q07820
Observed MW
37 kDa
Application
Tested Applications
ELISA, WB, IF, IHC
Recommended dilution
WB: 1:1000-1:10000; IHC: 1:200-1:500; IF: 1:10-1:100
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab05053(MCL1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer using FNab05053(MCL1 antibody) at dilution of 1:50
Background
Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.