Products
LPCAT1 antibody
- Product Name
- LPCAT1 antibody
- Catalogue No.
- FNab04826
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG2a
- Clone ID
- 7E4
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- lysophosphatidylcholine acyltransferase 1
- Alternative Names
- AYTL2 antibody, PFAAP3 antibody
- UniProt ID
- Q8NF37
- Observed MW
- 55 kDa
Application
- Tested Applications
- ELISA, WB, IF, IHC
- Recommended dilution
- WB: 1:5000-1:50000; IHC: 1:50-1:500; IF: 1:20-1:200
Validated Images
PC-12, C6, Raw264.7, NIH/3T3 cells were subjected to SDS PAGE followed by western blot with FNab04826( LPCAT1 Antibody) at dilution of 1:10000
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab04826( LPCAT1 Antibody) at dilution of 1:200
- Background
- Possesses both acyltransferase and acetyltransferase activities(PubMed:16864775, PubMed:21498505). Activity is calcium-independent(By similarity). Mediates the conversion of 1-acyl-sn-glycero-3-phosphocholine(LPC) into phosphatidylcholine(PC)(PubMed:21498505). Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively(PubMed:16704971). May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology(PubMed:16864775). Involved in the regulation of lipid droplet number and size(PubMed:25491198).
