Products
LNX1 antibody
- Product Name
- LNX1 antibody
- Catalogue No.
- FNab04814
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ligand of numb-protein X 1
- Alternative Names
- LNX antibody, PDZRN2 antibody
- UniProt ID
- Q8TBB1
- Observed MW
- 70 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500-1:2000
Validated Images
mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab04814(LNX1 antibody) at dilution of 1:100
- Background
- E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65(By similarity). Isoform 2 provides an endocytic scaffold for IGSF5/JAM4.
