Products
LGI1 antibody
- Product Name
- LGI1 antibody
- Catalogue No.
- FNab04760
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- leucine-rich, glioma inactivated 1
- Alternative Names
- EPT antibody
- UniProt ID
- O95970
- Observed MW
- 64 kDa, 58 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:50-1:200
Validated Images
human brain tissue were subjected to SDS PAGE followed by western blot with FNab04760(LGI1 antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab04760(LGI1 Antibody) at dilution of 1:50
- Background
- Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors(By similarity). Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway. May play a role in the control of neuroblastoma cell survival.
