Products

leptin antibody

Synonyms:FLJ94114 antibody, LEP antibody, leptin antibody, OB antibody, Obese protein antibody, Obesity factor antibody, OBS antibody
Catalogue No.:FNab04754Reativity:Human, Mouse
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
leptin antibody
Catalogue No.
FNab04754
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
leptin
Alternative Names
FLJ94114 antibody, LEP antibody, leptin antibody, OB antibody, Obese protein antibody, Obesity factor antibody, OBS antibody
UniProt ID
P41159
Observed MW
16 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:50-1:500
Validated Images
human adipose tissue were subjected to SDS PAGE followed by western blot with FNab04754(LEP antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human testis tissue slide using FNab04754(LEP Antibody) at dilution of 1:50
Background
Leptin is a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. Leptin is the most critical hormone in the homeostatic regulation of energy balance among those so far discovered. Leptin primarily acts on the neurons of the mediobasal part of hypothalamus to regulate food intake, thermogenesis, and the blood glucose level. Leptin also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. Leptin has also been linked to type 2 diabetes mellitus development.