KRAS antibody

Synonyms:C K RAS antibody, c Ki ras antibody, GTPase KRas antibody, K Ras 2 antibody, K RAS2A antibody, K RAS2B antibody, K RAS4A antibody, K RAS4B antibody, KI RAS antibody, KRAS antibody, KRAS1 antibody, KRAS2 antibody, KRAS2B speicifc antibody, Krasa antibody, Krasb antibody, NS3 antibody, RASK2 antibody
Catalogue No.:FNab04641Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IP, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
KRAS antibody
Catalogue No.
FNab04641
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Alternative Names
C K RAS antibody, c Ki ras antibody, GTPase KRas antibody, K Ras 2 antibody, K RAS2A antibody, K RAS2B antibody, K RAS4A antibody, K RAS4B antibody, KI RAS antibody, KRAS antibody, KRAS1 antibody, KRAS2 antibody, KRAS2B speicifc antibody, Krasa antibody, Krasb antibody, NS3 antibody, RASK2 antibody
UniProt ID
P01116
Observed MW
21 kDa
Application
Tested Applications
ELISA, WB, IP, IHC
Recommended dilution
WB: 1:500 - 1:1000; IHC: 1:50 - 1:200; IP: 1:50 - 1:200
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab04641(KRAS antibody) at dilution of 1:1000
IP result of anti-KRAS(IP:FNab04641, 4ug; Detection:FNab04641 1:1000) with HeLa cells lysate 2680 ug
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab04641(KRAS Antibody) at dilution of 1:100
Background
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation(PubMed:23698361, PubMed:22711838). Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes(TSGs) in colorectal cancer(CRC) cells in a ZNF304-dependent manner(PubMed:24623306).