HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab04557(KIF20A antibody) at dilution of 1:500
IP Result of anti-KIF20A (IP:FNab04557, 4ug; Detection:FNab04557 1:500) with HEK-293 cells lysate 1200ug.
Background
Mitotic kinesin required for chromosome passenger complex(CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate(GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility.