Products
JUN antibody
- Product Name
- JUN antibody
- Catalogue No.
- FNab04454
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- jun oncogene
- Alternative Names
- Activator protein 1 antibody, AP 1 antibody, AP1 antibody, c Jun antibody, JUN antibody, jun oncogene antibody, P39 antibody, Proto oncogene c Jun antibody, Transcription factor AP 1 antibody
- UniProt ID
- P05412
- Observed MW
- 39 kDa
Application
- Tested Applications
- ELISA, WB, IF, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab04454(JUN Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab04454(JUN Antibody) at dilution of 1:50
Immunofluorescent analysis of NIH/3T3 cells using FNab04454 (JUN antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG
- Background
- Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer(CRC) cells(PubMed:24623306). Binds to the USP28 promoter in colorectal cancer(CRC) cells(PubMed:24623306).
