SH-SY5Y cells were subjected to SDS PAGE followed by western blot with FNab04329(INPP5E antibody) at dilution of 1:1000
IP Result of anti-INPP5E (IP:FNab04329, 3ug; Detection:FNab04329 1:1000) with HEK-293 cells lysate 1000ug.
Immunohistochemistry of paraffin-embedded human testis using FNab04329(INPP5E antibody) at dilution of 1:50
Background
Converts phosphatidylinositol 3,4,5-trisphosphate(PtdIns 3,4,5-P3) to PtdIns-P2, and phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate. Specific for lipid substrates, inactive towards water soluble inositol phosphates.