IL 1 alpha antibody

Synonyms:IL-1A antibody, IL1 antibody, IL1-ALPHA antibody, IL1F1 antibody
Catalogue No.:FNab04208Reactivity:Human, Mouse
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
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Product Name
IL 1 alpha antibody
Catalogue No.
FNab04208
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
interleukin 1, alpha
Alternative Names
IL-1A antibody, IL1 antibody, IL1-ALPHA antibody, IL1F1 antibody
UniProt ID
P01583
Observed MW
35kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
H460 cells were subjected to SDS PAGE followed by western blot with FNab04208(IL1A antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse brain using FNab04208 (IL1A) at dilution of 1:100
Background
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.