Products
FGD5 antibody
- Product Name
- FGD5 antibody
- Catalogue No.
- FNab03086
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- FYVE, RhoGEF and PH domain containing 5
- Alternative Names
- FGD5 antibody, ZFYVE23 antibody
- UniProt ID
- Q6ZNL6
- Observed MW
- 160 kDa
Application
- Tested Applications
- ELISA, WB, IF, IHC
- Recommended dilution
- WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab03086(FGD5 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human lung using FNab03086(FGD5 antibody) at dilution of 1:100
Immunofluorescent analysis of Hela cells, using FGD5 antibody FNab03086(FGD5 antibody) at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Background
- Activates CDC42, a member of the Ras-like family of Rho-and Rac proteins, by exchanging bound GDP for free GTP. Mediates VEGF-induced CDC42 activation. May regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation. May play a role in regulating the actin cytoskeleton and cell shape.
