Products
FADS1 antibody
- Product Name
- FADS1 antibody
- Catalogue No.
- FNab02943
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- fatty acid desaturase 1
- Alternative Names
- FADSD5 antibody
- UniProt ID
- O60427
- Observed MW
- 52 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab02943(FADS1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using FNab02943(FADS1 Antibody) at dilution of 1:200
- Background
- Isoform 2 does not exhibit any catalytic activity toward 20:3n-6, but it may enhance FADS2 activity(By similarity). Isoform 1 is a component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids(HUFA) from precursor essential polyunsaturated fatty acids(PUFA) linoleic acid(LA)(18:2n-6) and alpha-linolenic acid(ALA)(18:3n-3). Catalyzes the desaturation of dihomo-gamma-linoleic acid(DHGLA)(20:3n-6) and eicosatetraenoic acid(20:4n-3) to generate arachidonic acid(AA)(20:4n-6) and eicosapentaenoic acid(EPA)(20:5n-3), respectively.
