Products
DCX antibody
- Product Name
- DCX antibody
- Catalogue No.
- FNab02280
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- doublecortin
- Alternative Names
- DBCN antibody, DC antibody, DCX antibody, doublecortin antibody, Doublin antibody, Lis X antibody, Lissencephalin X antibody, LISX antibody, SCLH antibody, XLIS antibody
- UniProt ID
- O43602
- Observed MW
- 40 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500-1:2000; IF: 1:20-1:200; IHC: 1:20-1:200
Validated Images
human brain tissue were subjected to SDS PAGE followed by western blot with FNab02280(DCX antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human gliomas using FNab02280(DCX antibody) at dilution of 1:100
Immunofluorescent analysis of SH-SY5Y cells using FNab02280(DCX antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
- Background
- Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration.
