Products

TMEM173 antibody

Synonyms:ERIS antibody, hMITA antibody, hSTING antibody, MITA antibody, MPYS antibody, NET23 antibody, SAVI antibody, STING antibody
Catalogue No.:FNab10949Reativity:Human
Host:MouseTested Application:ELISA, WB, IHC
Clonality:monoclonalIsotype:IgG2b
  • SPECIFICATIONS
Product Name
TMEM173 antibody
Catalogue No.
FNab10949
Size
100μg
Form
liquid
Purification
Protein A+G purification
Purity
≥95% as determined by SDS-PAGE
Clonality
monoclonal
Isotype
IgG2b
Clone ID
1G9
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
transmembrane protein 173
Alternative Names
ERIS antibody, hMITA antibody, hSTING antibody, MITA antibody, MPYS antibody, NET23 antibody, SAVI antibody, STING antibody
UniProt ID
Q86WV6
Observed MW
39 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:1000 - 1:5000; IHC: 1:100 - 1:500
Validated Images
THP-1 cells were subjected to SDS PAGE followed by western blot with FNab10949(TMEM173 antibody) at dilution of 1:2000
Immunohistochemistry of paraffin-embedded human tonsillitis using FNab10949(TMEM173 antibody) at dilution of 1:200
Background
This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.