CTDSP1 antibody

Synonyms:NIF3 antibody, NLIIF antibody, SCP1 antibody
Catalogue No.:FNab02050Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
CTDSP1 antibody
Catalogue No.
FNab02050
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
CTD(carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
Alternative Names
NIF3 antibody, NLIIF antibody, SCP1 antibody
UniProt ID
Q9GZU7
Observed MW
33 kDa
Application
Tested Applications
ELISA, WB
Recommended dilution
WB: 1:500-1:2000
Validated Images
mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab02050( CTDSP1 Antibody) at dilution of 1:300
Background
Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain(CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.