CSNK1A1 antibody

Catalogue No.:FNab02020Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
CSNK1A1 antibody
Catalogue No.
FNab02020
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
casein kinase 1, alpha 1
UniProt ID
P48729
Observed MW
42-45 kDa
Application
Tested Applications
ELISA, WB, IF
Recommended dilution
WB: 1:500-1:2000; IF: 1:20-1:200
Validated Images
MCF7 cells were subjected to SDS PAGE followed by western blot with FNab02020(CSNK1A1 antibody) at dilution of 1:1000
Background
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis(PubMed:11955436, PubMed:1409656, PubMed:18305108). May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration(PubMed:23902688).