human brain tissue were subjected to SDS PAGE followed by western blot with FNab05538(NAGK antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human kidney tissue slide using FNab05538(NAGK antibody) at dilution of 1:200
Background
Converts endogenous N-acetylglucosamine(GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. Involved in the N-glycolylneuraminic acid(Neu5Gc) degradation pathway: although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded. Also has ManNAc kinase activity.