Products
CREM antibody
- Product Name
- CREM antibody
- Catalogue No.
- FNab01970
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- cAMP responsive element modulator
- Alternative Names
- CREM antibody, hCREM 2 antibody, ICER antibody, Inducible cAMP early repressor antibody
- UniProt ID
- Q03060
- Observed MW
- 36 kDa
Application
- Tested Applications
- ELISA, IHC, WB
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
rat testis tissue were subjected to SDS PAGE followed by western blot with FNab01970(CREM Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human prostate cancer using FNab01970(CREM antibody) at dilution of 1:50
- Background
- Transcriptional regulator that binds the cAMP response element(CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Plays a role in spermatogenesis and is involved in spermatid maturation(PubMed:10373550). Isoform 6: May play a role in the regulation of the circadian clock: acts as a transcriptional repressor of the core circadian component PER1 by directly binding to cAMP response elements in its promoter.
