HeLa cells were subjected to SDS PAGE followed by western blot with FNab01961(CREB1 antibody) at dilution of 1:1500
IP Result of anti-CREB1 (IP:FNab01961, 3ug; Detection:FNab01961 1:600) with HEK-293 cells lysate 2000ug.
Immunohistochemistry of paraffin-embedded human thyroid tissue slide using FNab01961(CREB1 Antibody) at dilution of 1:50
Background
Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element(CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.