SW480 cells were subjected to SDS PAGE followed by western blot with FNab01225(calretinin Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse kidney tissue slide using FNab01225(calretinin Antibody) at dilution of 1:100
Background
Calbindin 2 (calretinin), is an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Calretinin is a useful marker for differentiating malignant mesothelioma from carcinomas.