Products
Antithrombin III antibody
- Product Name
- Antithrombin III antibody
- Catalogue No.
- FNab00448
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- serpin peptidase inhibitor, clade C(antithrombin), member 1
- Alternative Names
- Antithrombin antibody, Antithrombin III antibody, AT3 antibody, ATIII antibody, HEPARIN COFACTOR I antibody, Serpin C1 antibody, SERPINC1 antibody
- UniProt ID
- P01008
- Observed MW
- 53 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:200-1:1000; IF: 1:50-1:500
Validated Images
human blood tissue were subjected to SDS PAGE followed by western blot with FNab00448(SERPINC1 antibody) at dilution of 1:300
- Background
- SERPINC1, also named Antithrombin III or Antithrombin, is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
