Products

alpha 1 Antichymotrypsin / AACT antibody

Synonyms:A1 Antichymotrypsin antibody, AACT antibody, ACT antibody, Alpha 1 antichymotrypsin antibody, GIG24 antibody, GIG25 antibody, Serpin A3 antibody, SERPINA3 antibody
Catalogue No.:FNab00318Reativity:Human
Host:MouseTested Application:ELISA, WB, IHC
Clonality:monoclonalIsotype:IgG2b
  • SPECIFICATIONS
Product Name
alpha 1 Antichymotrypsin / AACT antibody
Catalogue No.
FNab00318
Size
100μg
Form
liquid
Purification
Protein A+G purification
Purity
≥95% as determined by SDS-PAGE
Clonality
monoclonal
Isotype
IgG2b
Clone ID
8F10
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
serpin peptidase inhibitor, clade A(alpha-1 antiproteinase, antitrypsin), member 3
Alternative Names
A1 Antichymotrypsin antibody, AACT antibody, ACT antibody, Alpha 1 antichymotrypsin antibody, GIG24 antibody, GIG25 antibody, Serpin A3 antibody, SERPINA3 antibody
UniProt ID
P01011
Observed MW
60 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:1000-1:10000; IHC: 1:20-1:300
Validated Images
human blood tissue were subjected to SDS PAGE followed by western blot with FNab00318(AACT antibody) at dilution of 1:5000
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab00318(AACT antibody) at dilution of 1:200
Background
Human SerpinA3, also known as Alpha 1-antichymotrypsin(AACT), is a member of the serine protease inhibitor class, and is a plasma alpha globulin glycoprotein which increases in the blood during the inflammatory process. SerpinA3, is also an inhibitor of neutrophil cathepsin G, mast cell chymases and pancreatic chymotrypsin. SerpinA3 is produced primarily in the liver, and is identified as an acute-phase inflammatory protein. SerpinA3 deficiency has been associated with liver disease. SerpinA3 has also been implicated in the pathology of a number of devastating human diseases including chronic obstructive pulmonary disease(COPD), Parkinson’s disease(PD), Alzheimer’s disease(AD), Stroke, Cystic Fibrosis, Cerebral Haemorrhage and Multiple System Atrophy.