Products
Aldolase C antibody
- Product Name
- Aldolase C antibody
- Catalogue No.
- FNab00303
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- aldolase C, fructose-bisphosphate
- Alternative Names
- ALDOC antibody, Aldolase C antibody, Brain type aldolase antibody, Fructose bisphosphate aldolase C antibody
- UniProt ID
- P09972
- Observed MW
- 39 kDa
Application
- Tested Applications
- ELISA, WB, IF
- Recommended dilution
- WB: 1:500-1:5000; IF: 1:10-1:100
Validated Images
mouse cerebellum tissue were subjected to SDS PAGE followed by western blot with FNab00303(ALDOC antibody) at dilution of 1:800
- Background
- Fructose-bisphosphate aldolase C(ALDOC) reversibly cleaves FBP and F1-P to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate and is strongly expressed in mammalian brain together with ALDOA and is alsopresent in the heart and spleen of some species(PMID:9363598). It is involed in glycolysis as an important enzyme. Phospholipase D2 and inositol 1,4,5-triphosphate interact with ALDOC in signal transduction. Meanwhile, the protein expression of ALDOC has been reported to be regulated in brain tumor, hepatomas, and lung cancer(PMID:21548097).
