Products
Integrin alpha 6 antibody
- Product Name
- Integrin alpha 6 antibody
- Catalogue No.
- FNab10271
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- integrin, alpha 6
- Alternative Names
- ITGA6 antibody, CD49f antibody, FLJ18737 antibody, Integrin alpha 6 antibody, ITGA6B antibody
- UniProt ID
- P23229
- Observed MW
- 120 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:200-1:2000
Validated Images
A549 cells were subjected to SDS PAGE followed by western blot with FNab10271(ITGA6 antibody) at dilution of 1:1000
- Background
- ITGA6, also named as CD49f and VLA-6, belongs to the integrin alpha chain family. It is a receptor for laminin on platelets. ITGA6 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome. Defects in ITGA6 are a cause of epidermolysis bullosa letalis with pyloric atresia(EB-PA) which also known as junctional epidermolysis bullosa with pyloric atresia(PA-JEB) or aplasia cutis congenita with gastrointestinal atresia.
