ADRP/Perilipin 2 antibody

Synonyms:ADFP antibody, Adipophilin antibody, ADRP antibody, Perilipin 2 antibody, PLIN2 antibody
Catalogue No.:FNab00184Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, IHC, IF, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
ADRP/Perilipin 2 antibody
Catalogue No.
FNab00184
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
adipose differentiation-related protein
Alternative Names
ADFP antibody, Adipophilin antibody, ADRP antibody, Perilipin 2 antibody, PLIN2 antibody
UniProt ID
Q99541
Observed MW
50 kDa
Application
Tested Applications
ELISA, IHC, IF, WB
Recommended dilution
WB: 1:1000-1:5000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
SW620 cells were subjected to SDS PAGE followed by western blot with FNab00184(ADRP Antibody) at dilution of 1:2000
Immunohistochemistry of paraffin-embedded human liver using FNab00184(ADRP antibody) at dilution of 1:100
Background
ADRP(adipocyte differentiation related protein) also known as ADFP, adipophilin, or perilipin-2, is a member of PAT family which is responsible for the transportation of lipids and the formation of lipid droplets. ADRP is localized on the surface of lipid droplets in a variety of tissues and cell lines. ADRP is not detected in undifferentiated cells but increases rapidly to high levels when adipocyte precursors differentiate into adipocytes. Anti-ADRP antibody is a reliable and sensitive marker for lipid droplet. Enhanced expression of ADRP is linked to diseases with abnormal lipid storage, including hepatic steatosis, atherosclerosis and diabetes. Immunohistochemistry of ADRP may facilitate histomorphological diagnosis of these diseases.