NIH/3T3 cells were subjected to SDS PAGE followed by western blot with FNab00140(ADAM19 Antibody) at dilution of 1:300
IP Result of anti-ADAM19 (IP:FNab00140, 4ug; Detection:FNab00140 1:300) with NIH/3T3 cells lysate 1200ug.
Background
Participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell. Also cleaves alpha-2 macroglobulin. May be involved in osteoblast differentiation and/or osteoblast activity in bone(By similarity).