KLHL3 antibody

Synonyms:KIAA1129 antibody
Catalogue No.:FNab04623Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
KLHL3 antibody
Catalogue No.
FNab04623
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
kelch-like 3(Drosophila)
Alternative Names
KIAA1129 antibody
UniProt ID
Q9UH77
Observed MW
65 kDa
Application
Tested Applications
ELISA, WB, IHC, IP
Recommended dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab04623(KLHL3 antibody) at dilution of 1:800
IP Result of anti-KLHL3 (IP:FNab04623, 4ug; Detection:FNab04623 1:700) with HepG2 cells lysate 2800ug.
Immunohistochemistry of paraffin-embedded human liver using FNab04623(KLHL3 antibody) at dilution of 1:100
Background
Substrate-specific adapter of a BCR(BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of ion transport in the distal nephron. The BCR(KLHL3) complex acts by mediating ubiquitination of WNK4, an inhibitor of potassium channel KCNJ1, leading to WNK4 degradation.