Products
CHRNE antibody
- Product Name
- CHRNE antibody
- Catalogue No.
- FNab10937
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- Acetylcholine receptor subunit epsilon
- Alternative Names
- CHRNE antibody, ACHRE antibody, CMS1D antibody, CMS1E antibody, CMS2A antibody, CMS4A antibody, CMS4B antibody, CMS4C antibody, FCCMS antibody, SCCMS antibody
- UniProt ID
- Q04844
- Observed MW
- 45 kDa
Application
- Tested Applications
- WB
- Recommended dilution
- WB: 1:500-1:2000
Validated Images
Various lysates were subjected to SDS PAGE followed by western blot with FNab10937( CHRNE Antibody) at dilution of 1:1000.
- Background
- Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. Mutations in the epsilon subunit are associated with congenital myasthenic syndrome.
