Products

anti- NME1 antibody

FNab10803 Catalogue No.
Synonyms
NDPKA, NM23
Host
Rabbit
Reactivity
Human, Rat
Isotype
IgG
Tested Application
ELISA, WB, IHC
Product Information
Product Name
anti- NME1 antibody
Catalogue No.
FNab10803
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background
This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
Immunogen Information
Immunogen
non-metastatic cells 1, protein (NM23A) expressed in
Synonyms
NDPKA, NM23
Observed MW
17 kDa
Application
Tested Application
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Uniprot information
UniProt ID
P15531
Images
Immunohistochemistry of paraffin-embedded rat lung using FNab10803(NME1 antibody) at dilution of 1:100
Various lysates were subjected to SDS PAGE followed by western blot with FNab10803(NME1 antibody) at dilution of 1:1000