CFHR3 antibody

Synonyms:CFHL3 antibody, DOWN16 antibody, FHR-3 antibody, FHR3 antibody, HLF4 antibody
Catalogue No.:FNab10775Reactivity:Human, Mouse
Host:RabbitTested Application:ELISA, WB, IHC, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
CFHR3 antibody
Catalogue No.
FNab10775
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
CFHR3
Alternative Names
CFHL3 antibody, DOWN16 antibody, FHR-3 antibody, FHR3 antibody, HLF4 antibody
UniProt ID
Q02985
Observed MW
45 kDa
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:50-1:100
Validated Images
Various lysates were subjected to SDS PAGE followed by western blot with FNab10775(CFHR3 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human kidney tissue slide using FNab10775(CFHR3 Antibody) at dilution of 1:100.
Background
The protein encoded by this gene is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.